Bismuth subsalicylat

CAS No. 14882-18-9

Bismuth subsalicylat( Bismuth oxide salicylate | Bismuth subsalicylate )

Catalog No. M12055 CAS No. 14882-18-9

Bismuth subsalicylate is used to treat diarrhea in adults and teenagers.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Bismuth subsalicylat
  • Note
    Research use only, not for human use.
  • Brief Description
    Bismuth subsalicylate is used to treat diarrhea in adults and teenagers.
  • Description
    Bismuth subsalicylate is used to treat diarrhea in adults and teenagers. It is also used to relieve the symptoms of an upset stomach, such as heartburn, indigestion, and nausea in adults and teenagers.
  • In Vitro
    ——
  • In Vivo
    In the gastrointestinal tract, Bismuth Subsalicylate can be converted to salicylic acid and insoluble bismuth salts. Salicylic acid reduces inflammation/irritation of stomach and intestinal lining through inhibition of prostaglandin G/H synthase 1/2.Bismuth Subsalicylate (oral gavage; 100 mg/kg-350 mg/kg) significantly decreases castor oil-induced movement of a charcoal test meal along the small intestine of the mouse and rat and also decreases both the fecal output (dry or wet weight) and the frequency of diarrhea in mice.
  • Synonyms
    Bismuth oxide salicylate | Bismuth subsalicylate
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX-1| COX-2
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    14882-18-9
  • Formula Weight
    362.09
  • Molecular Formula
    C7H5BiO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 0.04 mg/mL (0.11 mM)
  • SMILES
    O=C1O[Bi](O)OC2=CC=CC=C12
  • Chemical Name
    4H-1,3,2-Benzodioxabismin-4-one, 2-hydroxy-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Pitz AM, et al. Gut Microbes. 2015 Mar 4; 6(2):93-100.
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